Search results for "Spatial discrimination"

showing 2 items of 2 documents

Differential effects of age on subcomponents of response inhibition.

2013

Inhibitory deficits contribute to cognitive decline in the aging brain. Separating subcomponents of response inhibition may help to resolve contradictions in the existing literature. A total of 49 healthy participants underwent functional magnetic resonance imaging (fMRI) while performing a Go/no-go-, a Simon-, and a Stop-signal task. Regression analyses were conducted to identify correlations of age and activation patterns. Imaging results revealed a differential effect of age on subcomponents of response inhibition. In a simple Go/no-go task (no spatial discrimination), aging was associated with increased activation of the core inhibitory network and parietal areas. In the Simon task, whi…

AdultMaleAgingSpatial discriminationNeuropsychological TestsInhibitory postsynaptic potentialDevelopmental psychologyTask (project management)Young AdultmedicineReaction TimeAging brainHumansCognitive declineResponse inhibitionAgedmedicine.diagnostic_testGeneral NeuroscienceBrainMiddle AgedDifferential effectsMagnetic Resonance ImagingInhibition PsychologicalNeurology (clinical)Geriatrics and GerontologyFunctional magnetic resonance imagingPsychologyCognition DisordersNeuroscienceDevelopmental BiologyNeurobiology of aging
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Spatial discrimination thresholds for pain and touch in human hairy skin

2001

The traditional concept that pain is poorly localized has been challenged by recent studies, where subjects were able to point to the stimulated spot on the skin with an accuracy of 10-20 mm. Pointing movements themselves, however, have errors of about 15 mm. To determine the limits of sensory performance of the nociceptive system independent of motor performance, point localization of heat pain (540 mJ punctate laser stimuli, 5 mm diameter), mechanical pain (256 mN punctate probe, 200 microm diameter), and touch (16 mN von Frey probe, 1.1 mm diameter) were tested in a two-alternative forced-choice paradigm in 12 healthy subjects. Stimuli were applied in randomized order to two parallel lin…

AdultMalePain Thresholdmedicine.medical_specialtyHot TemperatureSpatial discriminationSensory systemParallelAngioplasty LaserDiscrimination PsychologicalPhysical StimulationmedicineNoxious stimulusHumansSkinPhysicsHairy skinMiddle AgedHandSurgeryAnesthesiology and Pain MedicineNociceptionNeurologyTouchReceptive fieldVon freyFemaleNeurology (clinical)HairBiomedical engineeringPain
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